Article

Whole-Exome Analysis Reveals X-linked Recessive Mutations underlying Premature Ovarian Failure Using Galaxy Platform<strong> </strong>

2021-05-21

Abstract excerpt

An in-silico WES approach using the Galaxy platform was adopted in the current study to predict the genetic basis of Premature Ovarian Failure (POF), where three affected patients in a Saudi Arabian family of seven, found associated with X-linked recessive mutations. The current analysis discovered 518,054 variants using FreeBayes variant caller that had 1,461,864 effects on variable sites in the genome revealed b...

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Literature Corpus work: 0d90cb5a-bab6-54d8-9444-3975bacbaa02
DOI: 10.20944/preprints202105.0519.v1

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