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Dupilumab dampens mucosal type 2 response during acetylsalicylic acid challenge in N-ERD patients

2024-06-07

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Rationale</h4> Non-steroidal anti-inflammatory drug-exacerbated respiratory disease (N-ERD) is characterized by the clinical triad of hypersensitivity to NSAIDs, nasal polyposis, and asthma. The cells and mediators causing acute symptoms when driving the hypersensitivity reaction to acetylsalicylic acid (ASA) ingestion, remain poorly defined. <h4>Objectives</h4> To investigate the dynamics of...

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Literature Corpus work
0cc9f63d-1e70-5aff-8d1f-a2e91d61c404
DOI
10.1101/2024.06.07.24308587
Open publication

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Dupilumab dampens mucosal type 2 response during acetylsalicylic acid challenge in N-ERD patientsDOI 10.1101/2024.06.07.24308587
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