Article

Population genomics of <i>Saccharomyces cerevisiae</i> human isolates: passengers, colonizers, invaders

2014-01-17

Abstract excerpt

The quest for the ecological niches of Saccharomyces cerevisiae ranged from wineries to oaks and more recently to the gut of Crabro Wasps. Here we propose the role of the human gut in shaping S. cerevisiae evolution, presenting the genetic structure of a previously unknown population of yeasts, associated with Crohn’s disease, providing evidence for clonal expansion within human’s gut. To understand the role of...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 0c30f925-b3b7-515d-99b4-4044ff2676f6
DOI: 10.1101/001891

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Population genomics of <i>Saccharomyces cerevisiae</i> human isolates: passengers, colonizers, invadersDOI 10.1101/001891Read

Comparative immunophenotyping of Saccharomyces cerevisiae and Candida spp. strains from Crohn’s disease patients and their interactions with the gut microbiomeSemantic proximity Read

Genome-wide association analysis of clinical vs. nonclinical origin provides insights into Saccharomyces cerevisiae pathogenesis.Semantic proximity Read

The 100-genomes strains, an S. cerevisiae resource that illuminates its natural phenotypic and genotypic variation and emergence as an opportunistic pathogen.Semantic proximity Read

Overview of the <i>Saccharomyces cerevisiae</i> population structure through the lens of 3,034 genomesSemantic proximity Read

Human commensal <i>Candida albicans</i> strains demonstrate substantial within-host diversity and retained pathogenic potentialSemantic proximity Read

Mining the Human Gut Microbiota for Effector Strains that Shape the Immune SystemSemantic proximity Read

Within-Host Genomic Diversity of Candida albicans in Healthy CarriersSemantic proximity Read

Dissecting the human microbiome with single-cell genomicsSemantic proximity Read

A Global Analysis of Mutations Accompanying Microevolution in the Heterozygous Diploid Pathogen <i>Candida albicans</i>Semantic proximity Read

Genomic and phenotypic comparison of <i>Saccharomyces cerevisiae</i> and <i>Saccharomyces boulardii</i>Semantic proximity Read

The Genome of the Human Pathogen <i>Candida albicans</i> is Shaped by Mutation and Cryptic Sexual RecombinationSemantic proximity Read

Population structure in a fungal human pathogen is potentially linked to pathogenicitySemantic proximity Read