Article

Spike protein of the SARS-CoV-2 omicron variant interacts with actin

2024-05-17

Abstract excerpt

The omicron variant of SARS-CoV-2 is responsible for the COVID-19 pandemic, serving as a significant origin for the variants still being detected today. It affects the spike protein that most vaccines used to target when the Omicron strain was discovered. Here, we demonstrate that the receptor binding domain (RBD) of the Omicron variant of SARS-CoV-2 exhibits an increased affinity for human angiotensin-converting...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 0c005f36-a904-574a-98d3-3c42126ee61b
DOI: 10.1101/2024.05.16.594608

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Spike protein of the SARS-CoV-2 omicron variant interacts with actinDOI 10.1101/2024.05.16.594608Read

Interaction of Receptor-Binding Domain of the SARS-CoV-2 Omicron Variant with hACE2 and Actin.Semantic proximity Read

Distinct Conformations of SARS-CoV-2 Omicron Spike Protein and Its Interaction with ACE2 and Antibody.Semantic proximity Read

Evolutionary trajectory of receptor binding specificity and promiscuity of the spike protein of SARS-CoV-2Semantic proximity Read

Analyzing the interaction of human ACE2 and RBD of spike protein of SARS-CoV-2 in perspective of Omicron variantSemantic proximity Read

Structural insights into the SARS-CoV-2 Omicron RBD-ACE2 interactionSemantic proximity Read

Molecular insights into the binding interactions and energetics of the omicron spike variant with hACE2 and a neutralizing antibody.Semantic proximity Read

Structural Basis for Human Receptor Recognition by SARS-CoV-2 Omicron Variant BA.1.Semantic proximity Read

Structural Insights of SARS-CoV-2 Spike Protein from Delta and Omicron VariantsSemantic proximity Read

Mutations on RBD of SARS-CoV-2 Omicron variant result in stronger binding to human ACE2 receptorSemantic proximity Read

Structural and functional impact by SARS-CoV-2 Omicron spike mutationsSemantic proximity Read

Structural and functional characterizations of infectivity and immune evasion of SARS-CoV-2 OmicronSemantic proximity Read

Atypical N-glycosylation of SARS-CoV-2 impairs the efficient binding of Spike-RBM to the human-host receptor hACE2Semantic proximity Read