Article

Gastrointestinal perforation following dabrafenib and trametinib administration in non-small cell lung carcinoma with BRAF V600E mutation: a case report and literature review

2021-04-02

Abstract excerpt

<title>Abstract</title> <p>Gastrointestinal perforation related to mitogen-activated protein kinase kinase (MEK) inhibitors has been reported previously; however, there has been no case report of such a condition in patients with non-small cell lung cancer (NSCLC). Herein, we report a case of small intestinal perforation secondary to dabrafenib and trametinib administration, but not related to tumor regression. A...

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Literature Corpus work: 0bc70edd-f03b-5103-b80f-45950c86b47c
DOI: 10.21203/rs.3.rs-323942/v1

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