Dramatic response of acute disseminated intravascular coagulation to erlotinib in a patient with lung adenocarcinoma with activating EGFR mutation.

doi:10.1177/0300060517720099

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Article

Dramatic response of acute disseminated intravascular coagulation to erlotinib in a patient with lung adenocarcinoma with activating EGFR mutation.

The Journal of international medical research - 1 Jan 2018

Kim Jung Soo, Ryu Jeong-Seon, Jeon Sang Hoon, Kim Hyun-Jung, Nam Hae-Seong, Cho Jae Hwa, Kwak Seung Min, Lee Hong Lyeol

Abstract excerpt

Disseminated intravascular coagulation (DIC) is a commonly encountered clinical situation characterized by thrombotic occlusion or bleeding in patients with lung cancer. DIC in patients with cancer is usually asymptomatic, taking a chronic form as a compensatory mechanism. Although acute DIC in patients with lung cancer is rarely reported, it can be fatal. We herein describe a patient with lung adenocarcinoma...

Topics

Adenocarcinoma
Adenocarcinoma of Lung
Aged, 80 and over
Antineoplastic Agents
Carcinoma, Basal Cell
Disseminated Intravascular Coagulation
ErbB Receptors
Erlotinib Hydrochloride
Gene Expression

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Humans

Lung Neoplasms

Male

Mutation

Protein Kinase Inhibitors

Treatment Outcome

Source

Open in PubMed Open full text

Identifiers

PMID: 28730909
DOI: 10.1177/0300060517720099
PMCID: PMC6011330

Genes

EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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