Article
Single-cell profiling of mosquito spermatogenesis defines the onset of meiotic silencing and pre-meiotic overexpression of the X chromosome.
2023-04-19
Abstract excerpt
<title>Abstract</title> <p>Understanding of the <italic>Anopheles gambiae</italic> germline has been essential to acquiring effective genetic control strategies targeting this malaria mosquito vector. This includes targeting germline genes to induce sterility or using regulatory sequences to drive transgene expression for applications such as gene drive. However, only very few germline regulatory elements have be...
Topics
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- Developmental Biology and Gene Regulation
- Epigenetics and DNA Methylation
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Renal and related cancers
- Reproductive Biology and Fertility
- Reproductive biology and impacts on aquatic species
- Single-cell and spatial transcriptomics
- Sperm and Testicular Function
Identifiers and source
- Literature Corpus work
- 0b6c3696-9b47-554e-8c42-6b686c42bb2f
- DOI
- 10.21203/rs.3.rs-2776581/v1
