Article

The Pga59 cell wall protein is an amyloid forming protein involved in adhesion and biofilm establishment in the pathogenic yeast Candida albicans.

2022-10-19

Abstract excerpt

<title>Abstract</title> The human commensal fungus <italic>Candida albicans</italic> can attach to epithelia or indwelling medical devices and form biofilms, that are highly tolerant to antifungal drugs and can evade the immune response. The cell surface protein Pga59 has been shown to influence adhesion and biofilm formation. Here, we present evidence that Pga59 displays amyloid properties. Using electron mic...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 0b6bd59e-6e7d-547e-9df3-82d67be0246d
DOI: 10.21203/rs.3.rs-2159129/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

The Pga59 cell wall protein is an amyloid forming protein involved in adhesion and biofilm establishment in the pathogenic yeast Candida albicans.DOI 10.21203/rs.3.rs-2159129/v1Read

Involvement of amyloid proteins in the formation of biofilms in the pathogenic yeast Candida albicansSemantic proximity Read

Integrated post-genomic cell wall analysis reveals floating biofilm formation associated with high expression of flocculins in the pathogen Candida kruseiSemantic proximity Read

Beyond the wall:Candida albicanssecret(e)s to surviveSemantic proximity Read

Amyloid-Like β-Aggregates as Force-Sensitive Switches in Fungal Biofilms and InfectionsSemantic proximity Read

Cell wall associated proteins involved in filamentation with impact on the virulence of Candida albicansSemantic proximity Read

Functional amyloids from bacterial biofilms – structural properties and interaction partnersSemantic proximity Read

The GPI-modified proteins Pga59 and Pga62 of Candida albicans are required for cell wall integritySemantic proximity Read

Functional regions of Candida albicans hyphal cell wall protein Als3 that determine interaction with the oral bacterium Streptococcus gordoniiSemantic proximity Read

Integrated post-genomic cell wall analysis reveals floating biofilm formation associated with high expression of flocculins in the pathogen Pichia kudriavzeviiSemantic proximity Read

Functional Redundancy in Candida auris Cell Surface Adhesins Crucial for Cell-Cell Interaction and AggregationSemantic proximity Read

The Terminal A Domain of the Fibrillar Accumulation-Associated Protein (Aap) of Staphylococcus epidermidis Mediates Adhesion to Human CorneocytesSemantic proximity Read

A role for amyloid in cell aggregation and biofilm formation.Semantic proximity Read