Article
Amyloid-Like β-Aggregates as Force-Sensitive Switches in Fungal Biofilms and Infections
29 Nov 2017
Abstract excerpt
SUMMARY Cellular aggregation is an essential step in the formation of biofilms, which promote fungal survival and persistence in hosts. In many of the known yeast cell adhesion proteins, there are amino acid sequences predicted to form amyloid-like β-aggregates. These sequences mediate amyloid formation in vitro. In vivo , these sequences mediate a phase transition from a disordered state to a partially ordered...
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