Article

<i>Pseudomonas aeruginosa</i> can diversify after host cell invasion to establish multiple intracellular niches

2022-10-08

Abstract excerpt

Within epithelial cells, Pseudomonas aeruginosa depends on its type three secretion system (T3SS) to escape vacuoles and replicate rapidly in the cytosol. Previously, it was assumed that intracellular subpopulations remaining T3SS-negative (and therefore in vacuoles) were destined for degradation in lysosomes, supported by data showing vacuole acidification. Here, we report in both corneal and bronchial human epi...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 0b5ee2f3-260c-57ab-aa18-a286278dd705
DOI: 10.1101/2022.10.07.511388

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

<i>Pseudomonas aeruginosa</i> can diversify after host cell invasion to establish multiple intracellular nichesDOI 10.1101/2022.10.07.511388Read

Molecular features underlying <i>Pseudomonas aeruginosa</i> persistence in human plasmaSemantic proximity Read

Goblet cell invasion promotes breaching of respiratory epithelia by an opportunistic human pathogenSemantic proximity Read

Exotoxin S secreted by internalized Pseudomonas aeruginosa delays lytic host cell death.Semantic proximity Read

Spatial lung niches shape <i>Pseudomonas aeruginosa</i> persistenceSemantic proximity Read

<i>In situ</i> profiling of bacterial growth activity during the early stages of <i>Pseudomonas aeruginosa</i> infection in airway epitheliaSemantic proximity Read

Infection dynamics and virulence potential of clinical <i>Pseudomonas aeruginosa</i> isolates in human airway epithelial modelsSemantic proximity Read

A Model of Intracellular Persistence of Pseudomonas aeruginosa in Airway Epithelial CellsSemantic proximity Read

Proteomic analysis of outer membrane vesicles derived from <i>Pseudomonas aeruginosa</i>Semantic proximity Read

Current concepts on Pseudomonas aeruginosa interaction with human airway epitheliumSemantic proximity Read

Pyocyanin disrupts airway regeneration to favor chronic <i>Pseudomonas aeruginosa</i> infectionSemantic proximity Read

Pseudomonas aeruginosa-Induced Bleb-Niche Formation in Epithelial Cells Is Independent of Actinomyosin Contraction and Enhanced by Loss of Cystic Fibrosis Transmembrane-Conductance Regulator Osmoregulatory FunctionSemantic proximity Read

<i>Pseudomonas aeruginosa</i> balances cytotoxicity and motility to counter phagocytosis by macrophagesSemantic proximity Read