Article

Prediction of Mutations and Outcome in Gastrointestinal Stromal Tumors with Deep Learning: A Multicenter, Multinational Study

2026-02-03

Abstract excerpt

<h4>Background</h4> Gastrointestinal stromal tumor (GIST) is the most common gastrointestinal mesenchymal tumor, driven by tyrosine-protein kinase KIT and platelet-derived growth factor receptor A (PDGFRA) mutations. Specific variants, such as KIT exon 11 deletions, carry prognostic and therapeutic implications, whereas wild-type (WT) variants derive limited benefit from tyrosine kinase inhibitors (TKIs). Given t...

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Literature Corpus work: 0b35f683-fb5a-5e09-93d1-48c480b81310
DOI: 10.64898/2026.02.02.26345350

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