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Integrated Bioinformatics Analysis and Clinical Validation Identify TNFSF14 and CD40 as Novel Biomarkers for Chronic Kidney Disease Progression and Tubulointerstitial Injury

2026-02-24

Abstract excerpt

<title>Abstract</title> <p>Background Chronic Kidney Disease (CKD) imposes a significant global health burden, defined by the irreversible loss of function and progressive fibrosis. There is a critical unmet need for non-invasive biomarkers that can accurately mirror renal inflammation and early-stage injury to guide diagnosis. This study combines bioinformatics with clinical validation to pinpoint pathogenic ge...

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Literature Corpus work
0ab5b8e9-8ee2-519d-8fbb-1cf0fce6f1e6
DOI
10.21203/rs.3.rs-8690385/v1
Open publication

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Integrated Bioinformatics Analysis and Clinical Validation Identify TNFSF14 and CD40 as Novel Biomarkers for Chronic Kidney Disease Progression and Tubulointerstitial InjuryDOI 10.21203/rs.3.rs-8690385/v1
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