Article

Uncovering Potential Biomarkers and Metabolic Pathways in Systemic Lupus Erythematosus and Lupus Nephritis through Integrated Microbiome and Metabolome Analysis

2025-04-08

Abstract excerpt

<title>Abstract</title> <p>Objective This study aimed to elucidate the relationship between gut microbiota and metabolomic profiles in patients with systemic lupus erythematosus (SLE) and lupus nephritis (LN) to identify potential biomarkers and elucidate their roles in disease progression. Methods Fecal samples from 15 healthy controls (HC) and 36 SLE patients (18 SLE-nonLN and 18 SLE-LN) were analyzed using 1...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 0a8aea23-44d9-56fe-8700-934722d70e78
DOI: 10.21203/rs.3.rs-5045051/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Uncovering Potential Biomarkers and Metabolic Pathways in Systemic Lupus Erythematosus and Lupus Nephritis through Integrated Microbiome and Metabolome AnalysisDOI 10.21203/rs.3.rs-5045051/v1Read

The bladder microbiome, metabolome, cytokines, and phenotypes in patients with systemic lupus erythematosusSemantic proximity Read

The Bladder Microbiome, Metabolome, Cytokines, and Phenotypes in Patients with Systemic Lupus Erythematosus.Semantic proximity Read

¹H NMR-based metabolomic study of metabolic profiling for systemic lupus erythematosus.Semantic proximity Read

The influence and therapeutic effect of microbiota in systemic lupus erythematosus.Semantic proximity Read

Outgrowth of Escherichia is susceptible to aggravation of systemic lupus erythematosusSemantic proximity Read

Proton pump inhibitors induce changes in the gut microbiome composition of systemic lupus erythematosus patientsSemantic proximity Read

Metagenome-wide association study revealed disease-specific landscape of the gut microbiome of systemic lupus erythematosus in JapaneseSemantic proximity Read

Multi-omics reveal mechanisms of action of gut microbes and metabolites in infantile cholestatic hepatopathySemantic proximity Read

Gut microbiota in systemic lupus erythematosus patients and lupus mouse model: a cross species comparative analysis for biomarker discoverySemantic proximity Read

Machine learning combined multi-omics analysis to explore key oxidative stress features in systemic lupus erythematosusSemantic proximity Read

Identification of a Shared Microbiomic and Metabolomic Profile in Systemic Autoimmune DiseasesSemantic proximity Read

Comprehensive Multi-omics Analysis Reveals the Core Role of Glycerophospholipid Metabolism in Rheumatoid Arthritis DevelopmentSemantic proximity Read