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The Bladder Microbiome, Metabolome, Cytokines, and Phenotypes in Patients with Systemic Lupus Erythematosus.

Microbiology spectrum - 26 Oct 2022

Liu Fengping, Du Jingjie, Zhai Qixiao, Hu Jialin, Miller Aaron W, Ren Tianli, Feng Yangkun, Jiang Peng, Hu Lei, Sheng Jiayi, Gu Chaoqun, Yan Ren, Lv Longxian, Wolfe Alan J, Feng Ninghan

Abstract excerpt

Emerging studies reveal unique bacterial communities in the human bladder, with alteration of composition associated to disease states. Systemic lupus erythematosus (SLE) is a complex autoimmune disease that is characterized by frequent impairment of the kidney. Here, we explored the bladder microbiome, metabolome, and cytokine profiles in SLE patients, as well as correlations between microbiome and metabolome,...

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Identifiers

PMID: 35913213
DOI: 10.1128/spectrum.00212-22
PMCID: PMC9620774

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