Article

Gene modules and non-coding RNAs involved in pancreatic tumorigenesis through acinar ductal metaplasia 

2020-11-20

Abstract excerpt

<h4>Background: </h4> Acinar ductal metaplasia (ADM) is a recently identified precursor lesion that can progress through pancreatic ductal intraepithelial neoplasia (PanIN) to pancreatic ductal adenocarcinoma (PDAC). However, the genetic alterations and the transcriptional regulators at work during the process of ADM-driven PDAC tumorigenesis are largely unknown. We applied a multidimensional integration strategy...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 0a7b1857-bdf9-5687-8d8c-a00082060a85
DOI: 10.21203/rs.3.rs-31936/v2

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Gene modules and non-coding RNAs involved in pancreatic tumorigenesis through acinar ductal metaplasia DOI 10.21203/rs.3.rs-31936/v2Read

Gene Expression Network Analysis of Precursor Lesions in Familial Pancreatic CancerSemantic proximity Read

Integrated bioinformatics analysis of potential biomarkers for pancreatic cancerSemantic proximity Read

Identification of novel genes associated with a poor prognosis in pancreatic ductal adenocarcinoma via a bioinformatics analysisSemantic proximity Read

Identification of new biomarkers for pancreatic cancer management: A bioinformatics analysisSemantic proximity Read

Investigation of Aberrantly Methylated Differentially Expressed Genes in Pancreatic Cancer by Integrated Bioinformatics AnalysisSemantic proximity Read

Integrated Bioinformatics Analysis of Gene Expression Profiles for Potential Biomarker Identification Towards Early Therapeutic Intervention in Pancreatitis and Pancreatic ductal adenocarcinomaSemantic proximity Read

A Novel miRNA–mRNA Axis Involves in Regulating Transcriptional Disorders in Pancreatic AdenocarcinomaSemantic proximity Read

Microarray expression profile analysis of long non-coding RNAs in pancreatic ductal adenocarcinomaSemantic proximity Read

Identification of potential target genes in pancreatic ductal adenocarcinoma by bioinformatics analysisSemantic proximity Read

Bioinformatic Analysis Suggests That Three Hub Genes May Be a Vital Prognostic Biomarker in Pancreatic Ductal AdenocarcinomaSemantic proximity Read

Identification of key hub genes in pancreatic ductal adenocarcinoma: an integrative bioinformatics studySemantic proximity Read

Transcriptional Profile of Human Pancreatic Acinar Ductal MetaplasiaSemantic proximity Read