Article

Exploring EPHB4 in Gait Disorders: VUS Detection and Phenotypic Characterization in a Toe-Walking Cohort

2025-09-23

Abstract excerpt

<title>Abstract</title> <p> <bold>Background:</bold> Idiopathic toe walking (ITW) is a gait anomaly with suspected genetic origins, though underlying mechanisms remain poorly understood. Although the established role of ephrin type-B receptor 4 (EPHB4) involves mainly vascular development, in this study we focused whether the detected variants might correlate with clinical findings in idiopathic toe walkers coh...

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Literature Corpus work: 09add86b-4a4e-59b3-a7a0-169b1c50a7ce
DOI: 10.21203/rs.3.rs-7343851/v1

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