Article

Timing and localization of myasthenia gravis-related gene expression

2021-01-06

Abstract excerpt

Myasthenia gravis (MG) is an acquired autoimmune disorder caused by autoantibodies binding acetylcholine receptors (AChR), muscle-specific kinase (MuSK), agrin or low-density lipoprotein receptor-related protein 4 (Lrp4). These autoantibodies inhibit neuromuscular transmission by blocking the function of these proteins, and thereby cause fluctuating skeletal muscle weakness. Several reports suggest that these auto...

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Literature Corpus work: 08f876ea-8ea1-5140-95ac-a0a605c0cf00
DOI: 10.1101/2021.01.05.425366

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