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Investigation of molecular modulation of taxane response in respiratory tract cancers by differential expression of mitotic spindle associated genes

2015-01-01

Abstract excerpt

Respiratory (Lung and head and neck) cancers contribute highly to the burden of cancer-related deaths. Taxanes are microtubule-targeting agents used to treat a variety of human cancers. Paclitaxel and Docetaxel represent the most prominent members of the taxane family, demonstrating significant activity mainly as part of complex chemotherapeutic regimens. Mitotic spindle formation and spindle checkpoint are critic...

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Literature Corpus work
08ea85af-30d9-59c7-8eb4-743d5328c152
DOI
10.17638/02037905
Open publication

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Investigation of molecular modulation of taxane response in respiratory tract cancers by differential expression of mitotic spindle associated genesDOI 10.17638/02037905
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