Article

Single Cell Raman Spectroscopy to Identify Different Stages of Proliferating Human Hepatocytes for Cell Therapy

2021-04-15

Abstract excerpt

<title>Abstract</title> <p><bold>Background: </bold>Cell therapy provides hope for treatment of advanced liver failure. Proliferating human hepatocytes (ProliHHs) were derived from primary human hepatocytes (PHH) and as potential alternative for cell therapy in liver diseases. Due to the continuous decline of mature hepatic genes and increase of progenitor like genes during ProliHHs expanding, it is challenge to...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 0802df05-7053-502f-a3a3-20f8bb2dba6e
DOI: 10.21203/rs.3.rs-421582/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Single Cell Raman Spectroscopy to Identify Different Stages of Proliferating Human Hepatocytes for Cell TherapyDOI 10.21203/rs.3.rs-421582/v1Read

Multi‐omics analysis of hiPSCs‐derived HLCs matured on‐chip revealed patterns typical of liver regenerationSemantic proximity Read

Generation of proliferating human adult hepatocytes using optimized 3D culture conditionsSemantic proximity Read

Noninvasive, Accurate Diagnosis of Chronic Liver Diseases Using Whole-Transcriptome Profiling of PlateletsSemantic proximity Read

Non-invasive Metabolomic Profiling of Embryo Culture Medium Using Raman Spectroscopy With Deep Learning Model Predicts the Blastocyst Development Potential of EmbryosSemantic proximity Read

Comparative Transcriptomic Analysis of Three Common Liver Cell LinesSemantic proximity Read

Isolation and Characterization of AFP+/DLK1+ Double-Positive Hepatic Stem/Progenitor Cells from Fibrotic PHx ModelSemantic proximity Read

Regenerative human liver organoids (HLOs) in a pillar/perfusion plate for hepatotoxicity assaysSemantic proximity Read

Human Hepatic Cell line 5 : In-Vitro Model for Hepatic ImmunobiologySemantic proximity Read

Dedifferentiation of Primary Hepatocytes is Accompanied with Reorganization of Lipid Metabolism Indicated by Altered Molecular Lipid and miRNA ProfilesSemantic proximity Read

Precursor of chemically expanded hepatocytes (pre-cHep) with 1-million-fold expansion potential and liver repopulation capacitySemantic proximity Read

HepaSH cells: Experimental human hepatocytes with lesser inter-individual variation and more sustainable availability than primary human hepatocytesSemantic proximity Read

A two-step lineage reprogramming strategy to generate functionally competent human hepatocytes from fibroblastsSemantic proximity Read