Article

The impact of mutations on the structural and functional properties of SARS-CoV-2 proteins: A comprehensive bioinformatics analysis

2021-03-01

Abstract excerpt

An in-depth analysis of first wave SARS-CoV-2 genome is required to identify various mutations that significantly affect viral fitness. In the present study, we have performed comprehensive in-silico mutational analysis of 3C-like protease (3CLpro), RNA dependent RNA polymerase (RdRp), and spike (S) proteins with the aim of gaining important insights into first wave virus mutations and their functional and structu...

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Literature Corpus work: 07b5799c-8961-5272-ad3d-9d1c7b745823
DOI: 10.1101/2021.03.01.433340

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