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Comparative mutational analysis of SARS-CoV-2 isolates from Pakistan and structural-functional implications using computational modelling and simulation approaches.

Computers in biology and medicine - 1 Feb 2022

Shah Abdullah, Rehmat Saira, Aslam Iqra, Suleman Muhmmad, Batool Farah, Aziz Abdul, Rashid Farooq, Midrarullah, Nawaz Muhmmad Asif, Ali Syed Shujait, Junaid Muhammad, Khan Abbas, Wei Dong-Qing

Abstract excerpt

SARS-CoV-2, an RNA virus, has been prone to high mutations since its first emergence in Wuhan, China, and throughout its spread. Its genome has been sequenced continuously by many countries, including Pakistan, but the results vary. Understanding its genomic patterns and connecting them with phenotypic features will help in devising therapeutic strategies. Thus, in this study, we explored the mutation landscape...

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Identifiers

PMID: 34968862
DOI: 10.1016/j.compbiomed.2021.105170
PMCID: PMC8709794

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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