Mechanism of autophagy induced by activation of the AMPK/ERK/mTOR signaling pathway after TRIM22-mediated DENV-2 infection of HUVECs

Abstract excerpt

<title>Abstract</title> <p> Background Dengue virus type 2 (DENV-2) was used to infect primary human umbilical vein endothelial cells (HUVECs) to examine autophagy induced by activation of the adenosine monophosphate-activated protein kinase (AMPK)/extracellular signal-regulated kinase (ERK)/mammalian target of rapamycin (mTOR) signaling pathway following tripartite motif-containing 22 (TRIM22)-mediated DENV-2...

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• Autophagy in Disease and Therapy
• Endoplasmic Reticulum Stress and Disease
• HIV Research and Treatment
• Insect symbiosis and bacterial influences
• Mosquito-borne diseases and control
• Studies on Chitinases and Chitosanases

Identifiers and source

Literature Corpus work

078150af-e474-5bfc-af80-b6b6fc32d3f3

DOI

10.21203/rs.3.rs-1648872/v2