Back to search

Article

Potential Inhibitors of EGFR Tyrosine Kinase from <em>Scutellaria baicalensis</em>: A Cheminformatics and Molecular Docking Studies

2022-09-15

Abstract excerpt

Epidermal Growth Factor Receptor (EGFR) tyrosine kinase is a cell surface receptor whose overexpression has been associated with different types of cancers including brain cancer (glioblastoma multiforme). The ability of the extract of Scutellaria baicalensis to inhibit the proliferation of malignant glioma cells have been reported. Thus, in this study we report the identification of 307 bioactive constituents res...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
070fbaed-21b8-5117-9cec-5d3b0a0ff9cd
DOI
10.20944/preprints202209.0218.v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Potential Inhibitors of EGFR Tyrosine Kinase from <em>Scutellaria baicalensis</em>: A Cheminformatics and Molecular Docking StudiesDOI 10.20944/preprints202209.0218.v1
Exploring Medicinal Mechanism of Baicalin in Tumor Microenvironment of Melanoma via Bioinformatic and In Vitro StudySemantic proximity
Exploring the therapeutic mechanisms and prognostic targets of Biochanin A in glioblastoma via integrated computational analysis and in vitro experimentsSemantic proximity
Exploring the Therapeutic Mechanisms and Prognostic Targets of Biochanin A in Glioblastoma via Network Pharmacology and Bioinformatics AnalysisSemantic proximity
Computational Analysis of Andrographolide and Berbamine for Targeting Glioblastoma Associated with Viral InfectionsSemantic proximity
An Integrated Pharmacoinformatics analysis on Prosopis juliflora bioactives to divulge EGFR-Mediated Crosstalk in the Gut–Brain AxisSemantic proximity
In silico identification of natural products from Traditional Chinese Medicine for cancer immunotherapySemantic proximity
Identification of potential edible spices as EGFR and EGFR mutant T790M/L858R inhibitors by structure-based virtual screening and molecular dynamics.Semantic proximity
Protein-Ligand Based Pharmacophore Approach against ERK5 Involved in Breast Cancer; In-Silico Study of Flavonoids from Blighia sapidaSemantic proximity
Unraveling the Role of Scutellaria baicalensis for the Treatment of Breast Cancer Using Network Pharmacology, Molecular Docking, and Molecular Dynamics SimulationSemantic proximity
A drug design strategy based on molecular docking and molecular dynamics simulations applied to development of inhibitor against triple-negative breast cancer by Scutellarein derivativesSemantic proximity
AURKB, CHEK1 and NEK2 as the Potential Target Proteins of Scutellaria barbata on Hepatocellular Carcinoma: An Integrated Bioinformatics AnalysisSemantic proximity
Discovery of Dual Inhibitors for Wild Type and D816V Mutant of c-KIT Kinase through Virtual and Biochemical Screening of Natural Products.Semantic proximity
Select a neighboring publication to make it the new centre.