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Exploring the therapeutic mechanisms and prognostic targets of Biochanin A in glioblastoma via integrated computational analysis and in vitro experiments

2024-02-15

Abstract excerpt

Abstract Glioblastoma (GBM) is the most aggressive brain tumor and is characterized by a poor prognosis and high recurrence and mortality rates. Biochanin A (BCA) exhibits promising clinical anti-tumor effects. In this study, we aimed to explore the pharmacological mechanisms by which BCA acts against GBM. Network pharmacology was employed to identify overlapping target genes between BCA and GBM. Differentially ex...

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Literature Corpus work
ac72ed65-653a-5ac8-a80b-89db798a9b86
DOI
10.1038/s41598-024-53442-0
Open publication

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Exploring the therapeutic mechanisms and prognostic targets of Biochanin A in glioblastoma via integrated computational analysis and in vitro experimentsDOI 10.1038/s41598-024-53442-0
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