Article

SARS-CoV-2 variants exhibit differential gut tropism and dysbiosis in Syrian golden hamsters

2023-06-19

Abstract excerpt

<h4>ABSTRACT</h4> Severe Acute Respiratory Syndrome Virus-2 (SARS-CoV-2) is a respiratory virus that uses angiotensin-converting enzyme 2 (ACE2) protein as an entry receptor. Thus, ACE2 expression levels in different tissues should dictate viral tropism. Notably, human ACE2 mRNA and protein levels are most abundant in the gastrointestinal tract, a pattern mirrored in Syrian golden hamsters. This prompted us to in...

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Literature Corpus work: 06facd9d-c719-52e6-9afc-9993392071a8
DOI: 10.1101/2023.06.19.545534

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