Article

Peripheral Blood Gene Expression Signatures Identify Methotrexate Responders in Patients with Rheumatoid Arthritis

2019-12-17

Abstract excerpt

<title>Abstract</title> <p>Background: Methotrexate (MTX) and biologic therapies have remarkably improved outcomes in patients with rheumatoid arthritis (RA). However, choices of therapeutic regimens in an individual patient remain empiric, resulting in a risk of delayed control of inflammation consequent joint damage. In previous studies we have shown that a large number of protein-coding genes are dysregulated...

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Literature Corpus work: 06869935-36d7-53d2-bc58-6775df2d1403
DOI: 10.21203/rs.2.19050/v1

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