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Article

Divergent gene activation in peripheral blood and tissues of patients with rheumatoid arthritis, psoriatic arthritis and psoriasis following infliximab therapy.

PloS one - 1 Jan 2014

Rosenberg Alexander, Fan Hongtao, Chiu Yahui G, Bolce Rebecca, Tabechian Darren, Barrett Rick, Moorehead Sharon, Baribaud Frédéric, Liu Hao, Peffer Nancy, Shealy David, Schwarz Edward M, Ritchlin Christopher T

Abstract excerpt

OBJECTIVE: The immune inflammatory disorders rheumatoid arthritis (RA), psoriatic arthritis (PsA) and psoriasis (Ps) share common pathologic features and show responsiveness to anti-tumor necrosis factor (TNF) agents yet they are phenotypically distinct. The aim of this study was to examine if anti-TNF therapy is associated with divergent gene expression profiles in circulating cells and target tissues of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 25333715
DOI: 10.1371/journal.pone.0110657
PMCID: PMC4204991

Genes

TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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