Article

A hidden Markov model reliably characterizes ketamine-induced spectral dynamics in macaque LFP and human EEG

2020-11-16

Abstract excerpt

Ketamine is an NMDA receptor antagonist commonly used to maintain general anesthesia. At anesthetic doses, ketamine causes bursts of 30-50 Hz oscillations alternating with 0.1 to 10 Hz oscillations. These dynamics are readily observed in local field potentials (LFPs) of non-human primates (NHPs) and electroencephalogram (EEG) recordings from human subjects. However, a detailed statistical analysis of these dynamic...

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Literature Corpus work: 06706610-c8e1-5f13-be30-22aff3a3a087
DOI: 10.1101/2020.11.12.20221366

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