Article

Process development using organic solvent nanofiltration (OSN) for oligonucleotide synthesis

2014-01-01

Abstract excerpt

Following the discovery of RNA interference (RNAi) and its exquisite control of protein expression, oligonucleotide (oligos) based drugs have been considered as the next generation of therapeutics, as they can deliver the treatment at the protein expression level. Oligos are short chains of nucleotides, typically 15-28 base-pairs long, synthesized in an iterative manner by sequential addition of nucleotide monomer...

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Literature Corpus work: 06027835-4a3b-5772-a38e-47bf3a82ef8e
DOI: 10.25560/45660

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