Article
Synaptic plasticity is altered by treatment with pharmacological levels of retinoic acid acting nongenomically however endogenous retinoic acid has not been shown to control synaptic plasticity
2021-12-09
Abstract excerpt
A paper recently published by eLife on forebrain cortical synaptic plasticity reports that retinoic acid (RA) alters synaptopodin-dependent metaplasticity in mouse dentate granule cells (Lenz et al., 2021). RA is the active form of vitamin A that functions as a ligand for nuclear RA receptors that directly bind genomic control regions to regulate gene expression (Chambon, 1996; Ghyselinck and Duester, 2019). Howev...
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Identifiers and source
- Literature Corpus work
- 04afcaf8-e12f-5889-bbed-e08792a90f0e
- DOI
- 10.20944/preprints202111.0412.v2