Back to search

Article

Tissue-guided LASSO for prediction of clinical drug response using preclinical samples

2019-08-05

Abstract excerpt

<h4>ABSTRACT</h4> Prediction of clinical drug response (CDR) of cancer patients, based on their clinical and molecular profiles obtained prior to administration of the drug, can play a significant role in individualized medicine. Machine learning models have the potential to address this issue, but training them requires data from a large number of patients treated with each drug, limiting their feasibility. Whil...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
044dcdec-49b3-5e29-9d8b-500ec9d379a9
DOI
10.1101/724310
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Tissue-guided LASSO for prediction of clinical drug response using preclinical samplesDOI 10.1101/724310
Select a neighboring publication to make it the new centre.