Article

Dopamine receptor D2 (DRD2) and dopamine transporter (DAT) gene promoter methylation and hyperphagia-related behavior in Prader-Willi syndrome

2022-07-25

Abstract excerpt

BACKGROUNDPrader-Willi syndrome (PWS), a neurodevelopmental disorder resulting from the loss of paternally derived but maternally imprinted genes in chromosomal region 15q11-13, is typically associated with marked hyperphagia leading to massive obesity if food intake is not controlled. The hyperphagia-related behavior is currently attributed mainly to dysregulation of hypothalamic signaling pathways, but recently...

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Literature Corpus work: 040e6960-aefd-55a2-96a1-ebfa98c566d2
DOI: 10.21203/rs.3.rs-1886109/v1

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