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Article

Advances in genetic mechanisms of hypothalamic dysfunction in Prader-Willi syndrome.

Yi chuan = Hereditas - 20 Oct 2022

Wang Xin-Yuan, Sun Rui, Gao Yuan-Qing

Abstract excerpt

Prader-Willi syndrome (PWS) is a rare congenital developmental disorder mainly due to the absent expression of genes on the paternally inherited chromosome 15q11-q13 region. Most of the clinical symptoms of PWS are related to hypothalamic dysfunction, including hyperphagia, morbid obesity, mental retardation, and hypogonadism. However, the molecular genetic mechanism of PWS is not fully understood, especially the...

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Identifiers

PMID: 36384726
DOI: 10.16288/j.yczz.22-188

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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