Article
[Molecular background of the ABO blood group system].
Postepy higieny i medycyny doswiadczalnej (Online) - 16 Jan 2008
Smolarek Dorota, Krop-Watorek Anna, Waśniowska Kazimiera, Czerwiński Marcin
Abstract excerpt
The ABO human blood group system consists of A antigens, B antigens, and antibodies against these antigens. The antigenic determinants are synthesized in the Golgi apparatus by specific glycosyltransferases which transfer proper sugars to an oligosaccharide acceptor, called H antigen. N-acetylgalactosaminotransferase (transferase A) uses a UDP-GalNac donor to convert the H antigen to A antigen, whereas...
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