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Article

Molecular genetic basis of the histo-blood group ABO system.

Nature - 17 May 1990

Yamamoto F, Clausen H, White T, Marken J, Hakomori S

Abstract excerpt

The histo-blood group ABO, the major human alloantigen system, involves three carbohydrate antigens (ABH). A, B and AB individuals express glycosyltransferase activities converting the H antigen into A or B antigens, whereas O(H) individuals lack such activity. Here we present a molecular basis for the ABO genotypes. The A and B genes differ in a few single-base substitutions, changing four amino-acid residues...

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Source

Identifiers

PMID: 2333095
DOI: 10.1038/345229a0

Genes

ABO

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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