Article

Uncovering expression signatures of synergistic drug response using an ensemble of explainable AI models

2021-10-07

Abstract excerpt

Complex machine learning models are poised to revolutionize the treatment of diseases like acute myeloid leukemia (AML) by helping physicians choose optimal combinations of anti-cancer drugs based on molecular features. While accurate predictions are important, it is equally important to be able to learn about the underlying molecular basis of anti-cancer drug synergy. Explainable AI (XAI) offers a promising new r...

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Literature Corpus work: 036f7de3-6e55-56cb-9486-eb23681be5af
DOI: 10.1101/2021.10.06.463409

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