Article

A Novel Digital Twin Strategy to Examine the Implications of Randomized Clinical Trials for Real-World Populations

2024-03-26

Abstract excerpt

<h4>ABSTRACT</h4> Randomized clinical trials (RCTs) are essential to guide medical practice; however, their generalizability to a given population is often uncertain. We developed a statistically informed Generative Adversarial Network (GAN) model, RCT-Twin-GAN, that leverages relationships between covariates and outcomes and generates a digital twin of an RCT (RCT-Twin) conditioned on covariate distributions fro...

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Radiomics and Machine Learning in Medical Imaging

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Literature Corpus work: 033dc840-f281-5ca7-849b-d2515cfae6ad
DOI: 10.1101/2024.03.25.24304868

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