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Deceased donor kidney degradomics indicates cytoskeletal proteolytic alterations impacting post-transplant function

2021-06-21

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> In brain death, cerebral injury contributes to systemic biological dysregulation, causing significant cellular stress in donor kidneys that adversely impacts the quality of grafts. Here, we hypothesized that DBD kidneys may undergo proteolytic processes that renders grafts susceptible to post-transplant dysfunction. <h4>Material & Methods</h4> Using mass spectrometry and immun...

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Literature Corpus work
02692a62-133e-5d08-845e-91afd6e13e64
DOI
10.1101/2021.06.10.21254305
Open publication

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Deceased donor kidney degradomics indicates cytoskeletal proteolytic alterations impacting post-transplant functionDOI 10.1101/2021.06.10.21254305
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