Article

Role of mitochondrial derived miR-1978 in nuclear genome

2024-07-02

Abstract excerpt

<title>Abstract</title> <p>We identified micro RNA (miR)-1978 that may originate from the mitochondrial genome, with a nucleotide sequence that perfectly matches the partial series of DHFR, KIF5C, and MSH3 genes of the nuclear genome. Overexpression of miR-1978 in the SHSY5Y cell line reduces DHFR, KIF5C, and MSH3 mRNA and protein expression, results in a division arrest in the G1 phase of the cell cycle, the num...

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Literature Corpus work: 0244a1b2-a1a1-5967-acad-a4e020f431a1
DOI: 10.21203/rs.3.rs-4446257/v1

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