Article
A developmental program that regulates mammalian organ size offsets evolutionary distance
2022-10-21
Abstract excerpt
Pigs are evolutionarily more distant from humans than mice, but their physiological organs are closest to humans. The molecular program leading to a more than 1,000-fold increase in organ size in pigs and humans over that of mice across evolution has not been elucidated. We generated large-scale transcriptional landscapes throughout swine lung development. Our cross-species single-cell molecular atlas let us disco...
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Identifiers and source
- Literature Corpus work
- 022050b4-bb98-54bf-92f1-17688bfe8be0
- DOI
- 10.1101/2022.10.19.512107