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Article

Oligogenic Causes of Human Differences of Sex Development: Facing the Challenge of Genetic Complexity.

Hormone research in paediatrics - 1 Jan 2023

Kouri Chrysanthi, Sommer Grit, Flück Christa E

Abstract excerpt

BACKGROUND: Deviations of intrauterine sex determination and differentiation and postnatal sex development can result in a very heterogeneous group of differences of sex development (DSD) with a broad spectrum of phenotypes. Variants in genes involved in sexual development cause different types of DSD, but predicting the phenotype from an individual's genotype and vice versa remains challenging. SUMMARY: Next...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34537773
DOI: 10.1159/000519691

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