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Establishing Population-Specific Thyroid-Stimulating Hormone Reference Intervals for Syrians: An Age- and Sex-Stratified Analysis Using Indirect Method

2026-04-18

Abstract excerpt

<h4>Background: </h4> Thyroid-stimulating hormone (TSH) reference intervals used in Syrian clinical laboratories are derived predominantly from Western or manufacturer-specified populations, without local validation. Given that TSH distributions are shaped by population-specific genetic architecture, iodine sufficiency, autoimmune burden, nutritional status, and chronic psychosocial stress—factors operating with p...

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Literature Corpus work
020e287e-2723-5136-97d1-ad932d1203b3
DOI
10.12688/f1000research.178247.1
Open publication

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