Article
MR imaging of familial Creutzfeldt-Jakob disease: a blinded and controlled study.
AJNR. American journal of neuroradiology - 1 Oct 2008
Fulbright R K, Hoffmann C, Lee H, Pozamantir A, Chapman J, Prohovnik I
Abstract excerpt
BACKGROUND AND PURPOSE: The E200K mutation of the PRNP (prion protein) gene is the most common cause of familial Creutzfeldt-Jakob disease (fCJD), which has imaging and clinical features that are similar to the sporadic form. The purpose of this study was to conduct a controlled and blinded evaluation of the sensitivity and specificity of MR imaging in this unique population. MATERIALS AND METHODS: We compared...
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