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Article

Cross-neutralization and viral fitness of SARS-CoV-2 Omicron sublineages

3 Jan 2023

Abstract excerpt

The rapid evolution of SARS-CoV-2 Omicron sublineages mandates a better understanding of viral replication and cross-neutralization among these sublineages. Here we used K18-hACE2 mice and primary human airway cultures to examine the viral fitness and antigenic relationship among Omicron sublineages. In both K18-hACE2 mice and human airway cultures, Omicron sublineages exhibited a replication order of BA.5 ≥ BA.2...

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PMID: 36594261
DOI: 10.1080/22221751.2022.2161422

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