Article

Estimating the burden of α-thalassaemia in Thailand using a comprehensive prevalence database for Southeast Asia

2018-09-12

Abstract excerpt

Severe forms of α-thalassaemia, haemoglobin H disease and haemoglobin Bart’s hydrops fetalis, are an important public health concern in Southeast Asia. Yet information on the prevalence, genetic diversity and health burden of α-thalassaemia in the region remains limited. We compiled a geodatabase of α-thalassaemia prevalence and genetic diversity surveys and, using geostatistical modelling methods, generated the f...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 01c65994-baa0-5d02-8638-9942668aa29c
DOI: 10.1101/412718

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Estimating the burden of α-thalassaemia in Thailand using a comprehensive prevalence database for Southeast AsiaDOI 10.1101/412718Read

Molecular spectrum of Hb H disease and characterization of rare deletional α-thalassemia found in ThailandSemantic proximity Read

A large cohort of Hb H disease in northeast Thailand: A molecular revisited, diverse genetic interactions and identification of a novel mutation.Semantic proximity Read

Molecular and hematological studies in a large cohort of α(0)-thalassemia in northeast Thailand: data from a single referral center.Semantic proximity Read

Revisiting and updating molecular epidemiology of α-thalassemia mutations in Thailand using MLPA and new multiplex gap-PCR for nine α-thalassemia deletion.Semantic proximity Read

Prevalence of α-thalassaemia genotypes in pregnant women in northern Thailand.Semantic proximity Read

A large cohort of deletional high hemoglobin F determinants in Thailand: A molecular revisited and identification of a novel mutation.Semantic proximity Read

Elevated Hemoglobin A2: A Molecular Revisited, and Implications to β-Thalassemia Screening.Semantic proximity Read

Survival and thalassaemia‐related complications in HbE /beta‐thalassaemia and alpha‐thalassaemia: A 10‐year longitudinal study in ThailandSemantic proximity Read

The prevalence and spectrum of alpha and beta thalassaemia in Guangdong Province: implications for the future health burden and population screening.Semantic proximity Read

Molecular epidemiology and hematological profiles of hemoglobin variants in southern Thailand.Semantic proximity Read

Molecular Characterization of Hb H and AEBart’s Diseases in Thai Children: Phramongkutklao Hospital Experiences.Semantic proximity Read

Enhancing Hemoglobin Bart's hydrops fetalis syndrome prevention: a single-tube multiplex real-time PCR assay for the comprehensive detection of four significant α0-thalassemia deletions (--SEA, --THAI, --CR, and --SA) found in Thailand.Semantic proximity Read