Kidney Function and Blood Pressure: A Bi-directional Mendelian Randomisation Study

Abstract excerpt

<h4>Objective</h4> To evaluate the bi-directional causal relation between kidney function and blood pressure. <h4>Design</h4> Mendelian randomisation study. <h4>Setting</h4> We performed two-sample Mendelian randomisation analyses. Genetic instruments of kidney function traits were selected from summary statistics of genome-wide association studies (GWAS) of glomerular filtration rate estimated from serum creat...

Topics

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• Birth, Development, and Health
• Cholesterol, HDL
• Genetic Associations and Epidemiology
• Glomerular Filtration Rate
• Kidney
• Mendelian Randomization Analysis
• Polymorphism, Single Nucleotide
• Pregnancy and preeclampsia studies

Identifiers and source

Literature Corpus work

01ada1ed-243f-5eea-9f75-8b346100adee

DOI

10.1101/856674