Back to search

Article

Thirteen tumor necrosis factor receptor superfamily gene expression in malignancies and their clinical relevance to immunotherapy: a pan-cancer analysis

2022-05-02

Abstract excerpt

<title>Abstract</title> <p><bold>Background:</bold> Although the expression of the tumor necrosis factor receptor superfamily (TNFRSF) genes and their anticancer functions in immune cells have been well described, little is known about the regulatory mechanisms and the clinical relevance of TNFRSF family gene expression in cancer cells. Recent studies indicate that the expression of CD40 (also known as TNFRSF5) i...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
019830de-db9d-539c-a8d6-29439d66fff7
DOI
10.21203/rs.3.rs-1598645/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Thirteen tumor necrosis factor receptor superfamily gene expression in malignancies and their clinical relevance to immunotherapy: a pan-cancer analysisDOI 10.21203/rs.3.rs-1598645/v1
Multi-omics Analysis of Tumor Necrosis Factor Superfamily 4 Reveals Its Prognostic Value and T Cell Exhaustion Feature in CancerSemantic proximity
Integrative single-cell profiling of melanoma reveals a tumor microenvironment signature predictive of immunotherapy responseSemantic proximity
Integrated analysis of polytranscriptomics reveals TNFSF ligand genes in pancreatic cancer prognosis and immune regulationSemantic proximity
Pan-cancer analysis of immune checkpoint receptors and ligands in various cells in the tumor immune microenvironmentSemantic proximity
TNFRSF12A is associated with immune cell infiltration in thyroid carcinomaSemantic proximity
Systematic evaluation of the predictive gene expression signatures of immune checkpoint inhibitors in metastatic melanomaSemantic proximity
The Identification and Validation of a Robust Immune-Associated Gene Signature in Cutaneous MelanomaSemantic proximity
TNFRSF12A Drives Triple-Negative Breast Cancer Progression via Immune Microenvironment Reprogramming and Facilitated AngiogenesisSemantic proximity
Construction and validation of a necroptosis-related gene signature associated with the tumor microenvironment in melanomaSemantic proximity
A four-gene signature predicts survival and anti-CTLA4 immunotherapeutic responses based on immune classification of melanomaSemantic proximity
Prediction of survival and immunotherapy response by the combined classifier of G protein-coupled receptors and tumor microenvironment in melanomaSemantic proximity
Hiding in the dark: pan-cancer characterization of expression and clinical relevance of CD40 to immune checkpoint blockade therapySemantic proximity
Select a neighboring publication to make it the new centre.