Article
Development of a novel startle response task in Duchenne muscular dystrophy
2021-09-13
Abstract excerpt
Duchenne muscular dystrophy (DMD), an X-linked childhood-onset muscular dystrophy caused by loss of the protein dystrophin, can be associated with neurodevelopmental, emotional and behavioural problems. A DMD mouse model also displays a neuropsychiatric phenotype, including increased startle responses to threat which normalise when dystrophin is restored in the brain. We hypothesised that startle responses may als...
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Identifiers and source
- Literature Corpus work
- 01689ff9-012f-5f83-968b-70f461e5ba7a
- DOI
- 10.1101/2021.09.06.21261840