Article

Pangenome analytics reveal two-component systems as conserved targets in ESKAPEE pathogens

2020-04-26

Abstract excerpt

Bacteria sense and respond to environmental stimuli through two-component systems (TCSs), that are composed of histidine kinase sensing and response regulator elements. TCSs are ubiquitous and participate in numerous cellular functions. TCSs across the ESKAPEE pathogens, representing the leading causes of nosocomial infections, were characterized using pangenome analytics, including annotation, mapping, pangenomic...

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Literature Corpus work: 0165935c-2fcf-513c-8865-6526384354b4
DOI: 10.1101/2020.04.25.061994

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