Article

A versatile high throughput strategy for cloning the env gene of HIV-1

2020-04-03

Abstract excerpt

The trimeric envelope glycoprotein (gp120/gp41) 3 of human immunodeficiency virus-1 (HIV-1) mediates viral and host cell membrane fusion, initiated by binding of viral envelope gp120 protein to the CD4 receptor on host immune cells. Functional env genes from infected individuals have been widely used as templates for vaccine design, for setting up viral neutralization assays and to study the viral evolution and p...

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Literature Corpus work: 0130e125-d1a0-59f2-acf0-4cfd2b0dd6c1
DOI: 10.1101/2020.04.01.020735

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